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Proteomic and functional analysis of Argonaute-containing mRNA–protein complexes in human cells

Members of the Argonaute (Ago) protein family associate with small RNAs and have important roles in RNA silencing. Here, we analysed Ago1- and Ago2-containing protein complexes in human cells. Separation of Ago-associated messenger ribonucleoproteins (mRNPs) showed that Ago1 and Ago2 reside in three...

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Main Authors: Höck, Julia, Weinmann, Lasse, Ender, Christine, Rüdel, Sabine, Kremmer, Elisabeth, Raabe, Monika, Urlaub, Henning, Meister, Gunter
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247381/
https://ncbi.nlm.nih.gov/pubmed/17932509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401088
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