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Polyclonal origin of mouse skin papillomas.

We show that, from the earliest morphologically recognisable stages of development, mouse skin papillomas induced by a chemical initiation-promotion regime are polyclonal. We have demonstrated polyclonality directly by immunohistochemical staining of the mosaic cell populations in embryo aggregation...

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Détails bibliographiques
Auteurs principaux: Winton, D. J., Blount, M. A., Ponder, B. A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247333/
https://ncbi.nlm.nih.gov/pubmed/2803917
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