Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy.

We report a systematic histopathologic study of papillomas at different times during promotion, correlating the results with those from cytogenetic analysis of the same tumors. Papillomas were induced in SENCAR mice by two-stage carcinogenesis (7,12-dimethylbenz[a]anthracene and phorbol 12-myristate...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Aldaz, C M, Conti, C J, Klein-Szanto, A J, Slaga, T J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.7.2029
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