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Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck.

Tumours of the head and neck were examined for gene amplification and expression of the epidermal growth factor (EGF) receptor by Southern blot and Western blot analyses. The EGF receptor gene was found to be amplified in four (19%) of 21 squamous cell carcinomas. The EGF receptor was overexpressed...

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Main Authors: Ishitoya, J., Toriyama, M., Oguchi, N., Kitamura, K., Ohshima, M., Asano, K., Yamamoto, T.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247138/
https://ncbi.nlm.nih.gov/pubmed/2713242
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