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Enhanced cytostatic activity of the sesquiterpene lactone eupatoriopicrin by glutathione depletion.

Eupatoriopicrin (EUP), a sesquiterpene lactone from Eupatorium cannabinum L., possesses cytostatic activity. This was demonstrated for FIO 26 cells in vitro with the aid of a clonogenic assay and in vivo by tumour growth delay in FIO 26 and Lewis lung tumour-bearing mice. In vitro the IC50 for 1 h e...

詳細記述

保存先:
書誌詳細
主要な著者: Woerdenbag, H. J., Lemstra, W., Malingré, T. M., Konings, A. W.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246971/
https://ncbi.nlm.nih.gov/pubmed/2757925
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