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Promotion of metastasis by a specific complex of coagulation factors may be independent of fibrin formation.

Coumarins inhibit metastasis in a number of animal models, but the mechanism of this effect remains unclear. We have investigated the relationship between the coagulation system and metastasis using a new model system, involving i.v. injection of Mtln3 rat mammary carcinoma cells into Fischer 344 ra...

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Main Authors: McCulloch, P., George, W. D.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1988
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246771/
https://ncbi.nlm.nih.gov/pubmed/3166906
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