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Caenorhabditis elegans WNK–STE20 pathway regulates tube formation by modulating ClC channel activity

WNK kinases are a small group of unique serine/threonine protein kinases that are conserved among multicellular organisms. Mutations in WNK1–4 cause pseudohypoaldosteronism type II—a form of hypertension. WNKs have been linked to the STE20 kinases and ion carriers, but the underlying molecular mecha...

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Detalhes bibliográficos
Main Authors: Hisamoto, Naoki, Moriguchi, Tetsuo, Urushiyama, Seiichi, Mitani, Shohei, Shibuya, Hiroshi, Matsumoto, Kunihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246628/
https://ncbi.nlm.nih.gov/pubmed/18049475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401128
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