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Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3

Oxidative stress plays a central role in many human diseases and in aging. In Caenorhabditis elegans the SKN-1 protein induces phase II detoxification gene transcription, a conserved oxidative stress response, and is required for oxidative stress resistance and longevity. Oxidative stress induces SK...

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Autori principali: An, Jae Hyung, Vranas, Kelly, Lucke, Michael, Inoue, Hideki, Hisamoto, Naoki, Matsumoto, Kunihiro, Blackwell, T. Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283458/
https://ncbi.nlm.nih.gov/pubmed/16251270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508105102
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