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Determining promoter location based on DNA structure first-principles calculations

A new method for the prediction of promoter regions based on atomic molecular dynamics simulations of small oligonucleotides has been developed. The method works independently of gene structure conservation and orthology and of the presence of detectable sequence features. Results obtained with our...

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Detalhes bibliográficos
Main Authors: Goñi, J Ramon, Pérez, Alberto, Torrents, David, Orozco, Modesto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246265/
https://ncbi.nlm.nih.gov/pubmed/18072969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-12-r263
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