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Specific Inhibition of the Synthesis of Human Lysyl-tRNA Synthetase Results in Decreases in tRNA(Lys) Incorporation, [Formula: see text] Annealing to Viral RNA, and Viral Infectivity in Human Immunodeficiency Virus Type 1
The major human tRNA(Lys) isoacceptors, [Formula: see text] and [Formula: see text] , are selectively packaged into human immunodeficiency virus type 1 (HIV-1) during assembly, where [Formula: see text] acts as a primer for reverse transcription. Lysyl-tRNA synthetase (LysRS) is also incorporated in...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC224598/ https://ncbi.nlm.nih.gov/pubmed/12941890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9817-9822.2003 |
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