Interleukin-15 and Natural Killer and NKT Cells Play a Critical Role in Innate Protection against Genital Herpes Simplex Virus Type 2 Infection

Interleukin-15 (IL-15), natural killer (NK) cells, and NK T (NKT) cells, components of the innate immune system, are known to contribute to defense against pathogens, including viruses. Here we report that IL-15(−/−) (NK(−) and NKT(−/+)) mice and RAG-2(−/−)/γ(c)(−/−) (NK(−) and NKT(−)) mice that lac...

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Bibliographic Details
Main Authors: Ashkar, Ali A., Rosenthal, Kenneth L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC224591/
https://ncbi.nlm.nih.gov/pubmed/12941930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10168-10171.2003
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