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Disruption of cellular translational control by a viral truncated eukaryotic translation initiation factor 2α kinase homolog

Phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) is a common cellular mechanism to limit protein synthesis in stress conditions. Baculovirus PK2, which resembles the C-terminal half of a protein kinase domain, was found to inhibit both human and yeast eIF2α kinases. Insect cell...

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Bibliografische gegevens
Hoofdauteurs: Dever, Thomas E., Sripriya, Rajaraman, McLachlin, Jeanne R., Lu, Jingfang, Fabian, John R., Kimball, Scot R., Miller, Lois K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22459/
https://ncbi.nlm.nih.gov/pubmed/9539707
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