Role of a critical water in scytalone dehydratase-catalyzed reaction
Scytalone dehydratase (EC 4.2.1.94) catalyzes the dehydration of two important intermediates in the biosynthesis of melanin, and it functions without metal ions or any cofactors. Using molecular orbital theory, we have examined the role of a critical water molecule in the mechanism of scytalone dehy...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1998
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4158 |
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