Assembly of an active enzyme by the linkage of two protein modules
The feasibility of creating new enzyme activities from enzymes of known function has precedence in view of protein evolution based on the concepts of molecular recruitment and exon shuffling. The enzymes encoded by the Escherichia coli genes purU and purN, N(10)-formyltetrahydrofolate hydrolase and...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1997
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1069 |
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