Combinations of Two Capsid Regions Controlling Canine Host Range Determine Canine Transferrin Receptor Binding by Canine and Feline Parvoviruses

Feline panleukopenia virus (FPV) and its host range variant, canine parvovirus (CPV), can bind the feline transferrin receptor (TfR), while only CPV binds to the canine TfR. Introducing two CPV-specific changes into FPV (at VP2 residues 93 and 323) endowed that virus with the canine TfR binding prop...

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Bibliographische Detailangaben
Hauptverfasser: Hueffer, Karsten, Govindasamy, Lakshman, Agbandje-McKenna, Mavis, Parrish, Colin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC224579/
https://ncbi.nlm.nih.gov/pubmed/12941920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10099-10105.2003
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