Combinations of Two Capsid Regions Controlling Canine Host Range Determine Canine Transferrin Receptor Binding by Canine and Feline Parvoviruses

Feline panleukopenia virus (FPV) and its host range variant, canine parvovirus (CPV), can bind the feline transferrin receptor (TfR), while only CPV binds to the canine TfR. Introducing two CPV-specific changes into FPV (at VP2 residues 93 and 323) endowed that virus with the canine TfR binding prop...

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Bibliographic Details
Main Authors: Hueffer, Karsten, Govindasamy, Lakshman, Agbandje-McKenna, Mavis, Parrish, Colin R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC224579/
https://ncbi.nlm.nih.gov/pubmed/12941920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10099-10105.2003
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