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Distinguishing surface effects of calcium ion from pore-occupancy effects in Na(+) channels

The effects of calcium ion on the Na(+) activation gate were studied in squid giant axons. Saxitoxin (STX) was used to block ion entry into Na(+) channels without hindering access to the membrane surface, making it possible to distinguish surface effects of calcium from pore-occupancy effects. In th...

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Autor principal: Armstrong, C. M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC22437/
https://ncbi.nlm.nih.gov/pubmed/10097180
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