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Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7

Stx2 is a protein toxin whose catalytic subunit acts as an N-glycosidase to depurinate a specific adenine base from 28S rRNA. In the holotoxin, the catalytic portion, A1, is linked to the rest of the A subunit, A2, and A2 interacts with the pentameric ring formed by the five B subunits. In order to...

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Detalhes bibliográficos
Main Authors: Fraser, Marie E., Cherney, Maia M., Marcato, Paola, Mulvey, George L., Armstrong, Glen D., James, Michael N. G.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242964/
https://ncbi.nlm.nih.gov/pubmed/16820678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106021968
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