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Purification, crystallization and X-ray diffraction analysis of human synaptotagmin 1 C2A-C2B
Synaptotagmin acts as the Ca(2+) sensor for neuronal exocytosis. The cytosolic domain of human synaptotagmin 1 is composed of tandem C2 domains: C2A and C2B. These C2 domains modulate the interaction of synaptotagmin with the phospholipid bilayer of the presynaptic terminus and effector proteins suc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Union of Crystallography
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242877/ https://ncbi.nlm.nih.gov/pubmed/16946482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106029253 |
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