Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1). There is a large body of evidence supporting a role for TRPV1 in noxious-mediated and inflammatory hyperalgesic responses. In this study, we evaluate...

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Hlavní autoři: Neubert, John K, Mannes, Andrew J, Karai, Laszlo J, Jenkins, Alan C, Zawatski, Lanel, Abu-Asab, Mones, Iadarola, Michael J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242785/
https://ncbi.nlm.nih.gov/pubmed/18199335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-3
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