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Structural Features of the Full-Length Adaptor Protein GADS in Solution Determined Using Small-Angle X-Ray Scattering()

The Grb2-related adaptor protein GADS plays a central role during the initial phases of signal transduction in T lymphocytes. GADS possesses N- and C-terminal Src homology 3 (SH3) domains flanking a central Src homology 2 (SH2) domain and a 126-residue region rich in glutamine and proline residues,...

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Bibliografiske detaljer
Main Authors: Moran, Oscar, Roessle, Manfred W., Mariuzza, Roy A., Dimasi, Nazzareno
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242750/
https://ncbi.nlm.nih.gov/pubmed/17993503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.116590
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