Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse

Infection with cagA-positive Helicobacter pylori is associated with gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma of B cell origin. The cagA-encoded CagA protein is delivered into gastric epithelial cells via the bacterial type IV secretion system and, upon tyr...

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Detalhes bibliográficos
Main Authors: Ohnishi, Naomi, Yuasa, Hitomi, Tanaka, Shinya, Sawa, Hirofumi, Miura, Motohiro, Matsui, Atsushi, Higashi, Hideaki, Musashi, Manabu, Iwabuchi, Kazuya, Suzuki, Misao, Yamada, Gen, Azuma, Takeshi, Hatakeyama, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242726/
https://ncbi.nlm.nih.gov/pubmed/18192401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711183105
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