Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells

Chronic infection with cagA-positive Helicobacter pylori is associated with the development of atrophic gastritis, peptic ulcers, and gastric adenocarcinoma. The cagA gene product CagA is injected into gastric epithelial cells, where it undergoes tyrosine phosphorylation by Src family kinases. Trans...

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Detalhes bibliográficos
Main Authors: Yokoyama, Kazuyuki, Higashi, Hideaki, Ishikawa, Susumu, Fujii, Yumiko, Kondo, Satoshi, Kato, Hiroyuki, Azuma, Takeshi, Wada, Akihiro, Hirayama, Toshiya, Aburatani, Hiroyuki, Hatakeyama, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172255/
https://ncbi.nlm.nih.gov/pubmed/15980153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502529102
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