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Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice

The role of the renin angiotensin system (RAS) in atherosclerosis is complex because of the involvement of multiple peptides and receptors. Renin is the rate-limiting enzyme in the production of all angiotensin peptides. To determine the effects of renin inhibition on atherosclerosis, we administere...

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Autori principali: Lu, Hong, Rateri, Debra L., Feldman, David L., Jr., Richard J. Charnigo, Fukamizu, Akiyoshi, Ishida, Junji, Oesterling, Elizabeth G., Cassis, Lisa A., Daugherty, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242618/
https://ncbi.nlm.nih.gov/pubmed/18274671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32970
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