Crystal structure of human peptidoglycan recognition protein Iα bound to a muramyl pentapeptide from Gram-positive bacteria

Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors of the innate immune system that bind bacterial peptidoglycans (PGNs). We determined the crystal structure, to 2.1 Å resolution, of the C-terminal PGN-binding domain of human PGRP-Iα in complex with a muramyl pentapeptide (...

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Hauptverfasser: Guan, Rongjin, Brown, Patrick H., Swaminathan, Chittoor P., Roychowdhury, Abhijit, Boons, Geert-Jan, Mariuzza, Roy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242522/
https://ncbi.nlm.nih.gov/pubmed/16641493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062077606
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