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Prevention of amyloid fibril formation of amyloidogenic chicken cystatin by site-specific glycosylation in yeast
To address the role of glycosylation on fibrillogenicity of amyloidogenic chicken cystatin, the consensus sequence for N-linked glycosylation (Asn(106)-Ile(108) → Asn(106)-Thr(108)) was introduced by site-directed mutagenesis into the wild-type and amyloidogenic chicken cystatins to construct the gl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242452/ https://ncbi.nlm.nih.gov/pubmed/16434741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051753306 |
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