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Enzymatic processing of collagen IV by MMP-2 (gelatinase A) affects neutrophil migration and it is modulated by extracatalytic domains

Proteolytic degradation of basement membrane influences the cell behavior during important processes, such as inflammations, tumorigenesis, angiogenesis, and allergic diseases. In this study, we have investigated the action of gelatinase A (MMP-2) on collagen IV, the major constituent of the basemen...

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Autores principales: Monaco, Susanna, Sparano, Valentina, Gioia, Magda, Sbardella, Diego, Di Pierro, Donato, Marini, Stefano, Coletta, Massimo
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242443/
https://ncbi.nlm.nih.gov/pubmed/17088321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062430706
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