Enzymatic processing of collagen IV by MMP-2 (gelatinase A) affects neutrophil migration and it is modulated by extracatalytic domains

Proteolytic degradation of basement membrane influences the cell behavior during important processes, such as inflammations, tumorigenesis, angiogenesis, and allergic diseases. In this study, we have investigated the action of gelatinase A (MMP-2) on collagen IV, the major constituent of the basemen...

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Main Authors: Monaco, Susanna, Sparano, Valentina, Gioia, Magda, Sbardella, Diego, Di Pierro, Donato, Marini, Stefano, Coletta, Massimo
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242443/
https://ncbi.nlm.nih.gov/pubmed/17088321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062430706
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