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Altered dynamics in Lck SH3 upon binding to the LBD1 domain of Herpesvirus saimiri Tip

The Tip protein from Herpesvirus saimiri interacts with the SH3 domain from the Src-family kinase Lck via a proline-containing sequence termed LBD1. Src-family kinase SH3 domains related to Lck have been shown to be dynamic in solution and partially unfold under physiological conditions. The rate of...

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Hlavní autoři: Weis, David D., Kjellen, Peter, Sefton, Bartholomew M., Engen, John R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242400/
https://ncbi.nlm.nih.gov/pubmed/17008721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052016406
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