Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development

Dlx homeobox genes are first expressed in embryonic retina at E11.5. The Dlx1/Dlx2 null retina has a reduced ganglion cell layer (GCL), with loss of late-born differentiated retinal ganglion cells (RGCs) due to increased apoptosis. TrkB signaling is proposed to regulate the dynamics of RGC apoptosis...

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Bibliographic Details
Main Authors: de Melo, Jimmy, Zhou, Qing-Ping, Zhang, Qi, Zhang, Shunzhen, Fonseca, Mario, Wigle, Jeffrey T., Eisenstat, David D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241891/
https://ncbi.nlm.nih.gov/pubmed/18086710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1099
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