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ATR-dependent pathways control hEXO1 stability in response to stalled forks
Nucleases play important roles in DNA synthesis, recombination and repair. We have previously shown that human exonuclease 1 (hEXO1) is phosphorylated in response to agents stalling DNA replication and that hEXO1 consequently undergoes ubiquitination and degradation in a proteasome-dependent manner....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2241874/ https://ncbi.nlm.nih.gov/pubmed/18048416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1052 |
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