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Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives

Ribonuclease P (RNase P) is a Mg(2+)-dependent endoribonuclease responsible for the 5′-maturation of transfer RNAs. It is a ribonucleoprotein complex containing an essential RNA and a varying number of protein subunits depending on the source: at least one, four and nine in Bacteria, Archaea and Euk...

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Detalhes bibliográficos
Main Authors: Kawamoto, Steven A., Sudhahar, Christopher G., Hatfield, Cynthia L., Sun, Jing, Behrman, Edward J., Gopalan, Venkat
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241863/
https://ncbi.nlm.nih.gov/pubmed/18084035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1088
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