Effects of zileuton and montelukast in mouse experimental spinal cord injury

BACKGROUND AND PURPOSE: 5-lipoxygenase (5-LO) is the key enzyme in leukotriene (LT) biosynthesis from arachidonic acid (AA). Here, we examined the role of the 5-LO-product, cysteinyl-LT (Cys-LT), with a 5-LO inhibitor (zileuton) and a Cys-LT, receptor antagonist (montelukast), in the inflammatory re...

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Main Authors: Genovese, T, Rossi, A, Mazzon, E, Di Paola, R, Muià, C, Caminiti, R, Bramanti, P, Sautebin, L, Cuzzocrea, S
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2007
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241786/
https://ncbi.nlm.nih.gov/pubmed/18059327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707577
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