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Normal Tissue Depresses While Tumor Tissue Enhances Human T Cell Responses In Vivo to a Novel Self/Tumor Melanoma Antigen, OA1

Antitumor T cells often recognize targets that are nonmutated “self” tissue differentiation Ags, but the relative impact of Ag expression by normal and transformed tissue for a human self/tumor Ag has not been studied. To examine the influence of self-tolerance mechanisms on the function of self/tum...

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Detalhes bibliográficos
Main Authors: Touloukian, Christopher E., Leitner, Wolfgang W., Schnur, Rhonda E., Robbins, Paul F., Li, Yong, Southwood, Scott, Sette, Alessandro, Rosenberg, Steven A., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241741/
https://ncbi.nlm.nih.gov/pubmed/12538723
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