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Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells

BACKGROUND: Recent incidents where highly pathogenic influenza A H5N1 viruses have spread from avian species into humans have prompted the development of cell-based production of influenza vaccines as an alternative to or replacement of current egg-based production. Madin-Darby canine kidney (MDCK)...

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Bibliografiske detaljer
Main Authors: Wang, Zhaoti, Duke, Gregory M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241602/
https://ncbi.nlm.nih.gov/pubmed/17956624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-102
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