Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β

Estrogen receptor (ER) modulators produce distinct tissue-specific biological effects, but within the confines of the established models of ER action it is difficult to understand why. Previous studies have suggested that there might be a relationship between ER structure and activity. Different ER...

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Autori principali: Paige, Lisa A., Christensen, Dale J., Grøn, Hanne, Norris, John D., Gottlin, Elizabeth B., Padilla, Karen M., Chang, Ching-yi, Ballas, Lawrence M., Hamilton, Paul T., McDonnell, Donald P., Fowlkes, Dana M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22409/
https://ncbi.nlm.nih.gov/pubmed/10097152
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