Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β

Estrogen receptor (ER) modulators produce distinct tissue-specific biological effects, but within the confines of the established models of ER action it is difficult to understand why. Previous studies have suggested that there might be a relationship between ER structure and activity. Different ER...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Paige, Lisa A., Christensen, Dale J., Grøn, Hanne, Norris, John D., Gottlin, Elizabeth B., Padilla, Karen M., Chang, Ching-yi, Ballas, Lawrence M., Hamilton, Paul T., McDonnell, Donald P., Fowlkes, Dana M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1999
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3999
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Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β

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