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Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma

Agonist ligands for the nuclear receptor peroxisome proliferator-activated receptor-γ have been shown to induce terminal differentiation of normal preadipocytes and human liposarcoma cells in vitro. Because the differentiation status of liposarcoma is predictive of clinical outcomes, modulation of t...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Demetri, George D., Fletcher, Christopher D. M., Mueller, Elisabetta, Sarraf, Pasha, Naujoks, Ryan, Campbell, Natalee, Spiegelman, Bruce M., Singer, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1999
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3951
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