Pharmacological Inhibition of CB(1) Cannabinoid Receptor Protects Against Doxorubicin-Induced Cardiotoxicity

OBJECTIVES: We aimed to explore the effects of pharmacologic inhibition of cannabinoid-1 (CB(1)) receptor in in vivo and in vitro models of doxorubicin (DOX)-induced cardiotoxicity. BACKGROUND: Doxorubicin is one of the most potent antitumor agents available; however, its clinical use is limited bec...

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Détails bibliographiques
Auteurs principaux: Mukhopadhyay, Partha, Bátkai, Sándor, Rajesh, Mohanraj, Czifra, Nora, Harvey-White, Judith, Haskó, György, Zsengeller, Zsuzsanna, Gerard, Norma P., Liaudet, Lucas, Kunos, George, Pacher, Pál
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239316/
https://ncbi.nlm.nih.gov/pubmed/17678736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2007.03.057
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