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Apoptotic Death of CD8(+) T Lymphocytes After Immunization: Induction of a Suppressive Population of Mac-1(+)/Gr-1(+) Cells

Following an infection or immunization, a primary CD8(+) T cell response generally rises then falls rapidly before giving rise to a “memory” response. When we immunized mice with recombinant viral immunogens optimized to enhance the lytic capability of CD8(+) T cells, we measured a profound depressi...

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Bibliografiske detaljer
Main Authors: Bronte, Vincenzo, Wang, Michael, Overwijk, Willem W., Surman, Deborah R., Pericle, Federica, Rosenberg, Steven A., Restifo, Nicholas P.
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239007/
https://ncbi.nlm.nih.gov/pubmed/9820504
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