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Domain motions of Argonaute, the catalytic engine of RNA interference

BACKGROUND: The Argonaute protein is the core component of the RNA-induced silencing complex, playing the central role of cleaving the mRNA target. Visual inspection of static crystal structures already has enabled researchers to suggest conformational changes of Argonaute that might occur during RN...

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Detalles Bibliográficos
Main Authors: Ming, Dengming, Wall, Michael E, Sanbonmatsu, Kevin Y
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238725/
https://ncbi.nlm.nih.gov/pubmed/18053142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-470
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