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The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends
Mycobacteria can repair DNA double-strand breaks (DSBs) via a nonhomologous end-joining (NHEJ) system that includes a dedicated DNA ligase (LigD) and the DNA end-binding protein Ku. Here we exploit an improved plasmid-based NHEJ assay and a collection of Mycobacterium smegmatis strains bearing delet...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238672/ https://ncbi.nlm.nih.gov/pubmed/18281464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1631908 |
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