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The pathways and outcomes of mycobacterial NHEJ depend on the structure of the broken DNA ends

Mycobacteria can repair DNA double-strand breaks (DSBs) via a nonhomologous end-joining (NHEJ) system that includes a dedicated DNA ligase (LigD) and the DNA end-binding protein Ku. Here we exploit an improved plasmid-based NHEJ assay and a collection of Mycobacterium smegmatis strains bearing delet...

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Detalhes bibliográficos
Main Authors: Aniukwu, Jideofor, Glickman, Michael S., Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238672/
https://ncbi.nlm.nih.gov/pubmed/18281464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1631908
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