DECREASED ENZYME ACTIVITIES OF CHAPERONES PDI AND BIP IN AGED MOUSE LIVERS

The endoplasmic reticulum (ER) is a target for endogenously generated reactive oxygen species (ROS) during aging. We have previously shown that the ER chaperones, protein disulfide isomerase (PDI) and immunoglobulin heavy chain binding protein (BiP) are oxidatively modified within the livers of aged...

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Main Authors: Nuss, Jonathan E., Choksi, Kashyap B., DeFord, James H., Papaconstantinou, John
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238339/
https://ncbi.nlm.nih.gov/pubmed/17996725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.10.194
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