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DECREASED ENZYME ACTIVITIES OF CHAPERONES PDI AND BIP IN AGED MOUSE LIVERS

The endoplasmic reticulum (ER) is a target for endogenously generated reactive oxygen species (ROS) during aging. We have previously shown that the ER chaperones, protein disulfide isomerase (PDI) and immunoglobulin heavy chain binding protein (BiP) are oxidatively modified within the livers of aged...

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Detalhes bibliográficos
Main Authors: Nuss, Jonathan E., Choksi, Kashyap B., DeFord, James H., Papaconstantinou, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238339/
https://ncbi.nlm.nih.gov/pubmed/17996725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.10.194
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