IL-18 Does not Increase Allergic Airway Disease in Mice When Produced by BCG

Whilst BCG inhibits allergic airway responses in murine models, IL-18 has adversary effects depending on its environment. We therefore constructed a BCG strain producing murine IL-18 (BCG-IL-18) and evaluated its efficiency to prevent an asthma-like reaction in mice. BALB/cByJ mice were sensitized (...

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Bibliografiske detaljer
Main Authors: Amniai, L., Biet, F., Marquillies, P., Locht, C., Pestel, J., Tonnel, A.-B., Duez, C.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2235931/
https://ncbi.nlm.nih.gov/pubmed/18299704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/67276
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