GADD45 induction of a G(2)/M cell cycle checkpoint

G(1)/S and G(2)/M cell cycle checkpoints maintain genomic stability in eukaryotes in response to genotoxic stress. We report here both genetic and functional evidence of a Gadd45-mediated G(2)/M checkpoint in human and murine cells. Increased expression of Gadd45 via microinjection of an expression...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Wang, Xin Wei, Zhan, Qimin, Coursen, Jill D., Khan, Mohammed A., Kontny, H. Udo, Yu, Lijia, Hollander, M. Christine, O’Connor, Patrick M., Fornace, Albert J., Harris, Curtis C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1999
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3706
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!