THE ENZYMATIC TERMINATION OF POLYDEOXYNUCLEOTIDES BY 2′,3′-DIDEOXYADENOSINE TRIPHOSPHATE

The nucleoside 2′,3′-dideoxyadenosine is lethal to E. coli and blocks DNA synthesis irreversibly. The hypothesis that a derived dideoxynucleoside triphosphate is incorporated terminally into the cellular DNA has been tested in an in vitro system. The triphosphate of dideoxyadenosine was synthesized...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Toji, Lorraine, Cohen, Seymour S.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1969
Matèries:	Biological Sciences: Biochemistry
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4899881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.63.3.871
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