Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer

The transcription factor Runx1/AML1 is an important regulator of hematopoiesis and is critically required for the generation of the first definitive hematopoietic stem cells (HSCs) in the major vasculature of the mouse embryo. As a pivotal factor in HSC ontogeny, its transcriptional regulation is of...

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Autors principals: Nottingham, Wade T., Jarratt, Andrew, Burgess, Matthew, Speck, Caroline L., Cheng, Jan-Fang, Prabhakar, Shyam, Rubin, Eddy M., Li, Pik-Shan, Sloane-Stanley, Jackie, Kong-a-San, John, de Bruijn, Marella F. T. R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2007
Matèries:
Hematopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234795/
https://ncbi.nlm.nih.gov/pubmed/17823307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-100883
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