Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma

Mutations of the TP53 tumor suppressor gene have been associated with poor survival in some series of diffuse large B-cell lymphoma (DLBCL) but not in other studies. The purpose of this study was to identify the frequency of TP53 alterations (mutations or deletions), characterize the gene expression...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Young, Ken H., Weisenburger, Dennis D., Dave, Bhavana J., Smith, Lynette, Sanger, Warren, Iqbal, Javeed, Campo, Elias, Delabie, Jan, Gascoyne, Randy D., Ott, German, Rimsza, Lisa, Müller-Hermelink, H. Konrad, Jaffe, Elaine S., Rosenwald, Andreas, Staudt, Louis M., Chan, Wing C., Greiner, Timothy C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Hematology 2007
Θέματα:
Neoplasia
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234786/
https://ncbi.nlm.nih.gov/pubmed/17881637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-02-072082
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